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Poly ADP-Ribose Polymerase 1 (PARP1) Antibody
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Catalogue No: abx031238
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Research Articles on Poly ADP-Ribose Polymerase 1 (PARP1)
| Target | Poly ADP-Ribose Polymerase 1 (PARP1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 123-151 amino acids from the N-terminal region of human PARP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09874 (UniProt, ExPASy) |
| UniProt Secondary AC | B1ANJ4, Q8IUZ9 |
| UniProt Entry Name | PARP1_HUMAN |
| KEGG | hsa:142 |
| String | 9606.ENSP00000355759 |
| Molecular Weight | Calculated MW: 113 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse PARP1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |