PARP1 (pT368) Antibody

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Catalogue No: abx032186
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Target PARP1 (pT368)
Clonality Polyclonal
Target Modification Thr368
Modification Phosphorylation
Reactivity Human
Tested Applications ELISA, DB
Host Rabbit
Recommended dilutions DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T368 of human PARP1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P09874 (UniProt, ExPASy)
UniProt Secondary AC B1ANJ4, Q8IUZ9
UniProt Entry Name PARP1_HUMAN
KEGG hsa:142
String 9606.ENSP00000355759
Molecular Weight Calculated MW: 113 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on PARP1 (pT368)


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