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Paired Box Protein Pax-6 (PAX6) Antibody
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Catalogue No: abx025234
Price:
US$290.00
(Size: 80 µl)
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This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].
Research Articles on Paired Box Protein Pax-6 (PAX6)
| Target | Paired Box Protein Pax-6 (PAX6) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human PAX6 recombinant protein. |
| Isotype | IgM Kappa |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P26367 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6N006, Q99413 |
| UniProt Entry Name | PAX6_HUMAN |
| KEGG | hsa:5080 |
| String | 9606.ENSP00000404100 |
| Molecular Weight | Calculated MW: 46.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow PAX6. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |