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Pre-B-Cell Colony-Enhancing Factor 1 (PBEF1) Antibody
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Catalogue No: abx011321
Price:
US$427.75
(Size: 100 µl)
Orders to United States ship from United States
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PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Research Articles on Pre-B-Cell Colony-Enhancing Factor 1 (PBEF1)
| Target | Pre-B-Cell Colony-Enhancing Factor 1 (PBEF1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P43490 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D0Q9, A4D0R0, Q3KQV0, Q8WW95 |
| UniProt Entry Name | NAMPT_HUMAN |
| Gene Symbol | NAMPT |
| GeneID | 10135 |
| OMIM | 608764 |
| HGNC | 30092 |
| KEGG | hsa:10135 |
| Ensembl | ENSG00000105835 |
| String | 9606.ENSP00000222553 |
| Molecular Weight | 56 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |