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Plasma Anticoagulant Protein C (PC) Antibody
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Catalogue No: abx026849
Price:
US$326.25
(Size: 80 µl)
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This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].
Research Articles on Plasma Anticoagulant Protein C (PC)
| Target | Plasma Anticoagulant Protein C (PC) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human PC. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P11498 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DN00, Q16705 |
| UniProt Entry Name | PYC_HUMAN |
| KEGG | hsa:5091 |
| String | 9606.ENSP00000377532 |
| Molecular Weight | Calculated MW: 130 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Cow PC. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |