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Plasma Anticoagulant Protein C (PC) Antibody
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Catalogue No: abx004816
Price:
US$348.00
(Size: 60 µl)
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PC Antibody is a Rabbit Polyclonal antibody against PC. This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
Research Articles on Plasma Anticoagulant Protein C (PC)
| Target | Plasma Anticoagulant Protein C (PC) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PC |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P11498 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DN00, Q16705 |
| UniProt Entry Name | PYC_HUMAN |
| Gene Symbol | PC |
| GeneID | 5091 |
| NCBI Accession | NP_001035806.1 |
| KEGG | hsa:5091 |
| String | 9606.ENSP00000377532 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |