Protocadherin Alpha 6 (PCDHA6) Antibody
REQUEST MORE INFO
Price:
US$203.00
(Size: 20 µl)
Click on the image to see the image legend
PCDHA6 Antibody is a Rabbit Polyclonal antibody against PCDHA6. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Target |
Protocadherin Alpha 6 (PCDHA6) |
Clonality |
Polyclonal |
Reactivity |
Human, Mouse, Rat |
Tested Applications |
WB, IF/ICC |
Host |
Rabbit |
Recommended dilutions |
WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation |
Unconjugated |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human PCDHA6. |
Isotype |
IgG |
Form |
Liquid |
Purification |
Purified by affinity chromatography. |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC |
Q9UN73 (UniProt,
ExPASy)
|
UniProt Secondary AC |
O75283, Q9NRT8 |
UniProt Entry Name |
PCDA6_HUMAN |
Gene Symbol |
PCDHA6 |
GeneID |
56142
|
NCBI Accession |
NP_061732.1
|
String |
9606.ENSP00000433378
|
Molecular Weight |
Calculated MW: 103 kDa Observed MW: 103 kDa |
Buffer |
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
Concentration |
> 0.2 mg/ml |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |
Research Articles on Protocadherin Alpha 6 (PCDHA6)