Protocadherin Gamma-C4 (PCDHGC4) Antibody
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Price:
US$290.00
(Size: 80 µl)
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This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Target |
Protocadherin Gamma-C4 (PCDHGC4) |
Clonality |
Polyclonal |
Reactivity |
Human |
Tested Applications |
ELISA, WB |
Host |
Rabbit |
Recommended dilutions |
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation |
Unconjugated |
Immunogen |
KLH-conjugated synthetic peptide between 265-291 amino acids from the N-terminal region of human PCDHGC4. |
Isotype |
IgG |
Form |
Liquid |
Purification |
Purified through a protein A column, followed by peptide affinity purification. |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC |
Q9Y5F7 (UniProt,
ExPASy)
|
UniProt Secondary AC |
Q495T2, Q9Y5C3 |
UniProt Entry Name |
PCDGL_HUMAN |
Gene Symbol |
PCDHGC4 |
String |
9606.ENSP00000306918
|
Molecular Weight |
Calculated MW: 101 kDa |
Buffer |
PBS containing 0.09% sodium azide. |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |
Research Articles on Protocadherin Gamma-C4 (PCDHGC4)