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Proliferating Cell Nuclear Antigen (PCNA) Antibody
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Catalogue No: abx000649
Price:
US$203.00
(Size: 20 µl)
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PCNA Antibody is a Rabbit Polyclonal antibody against PCNA. The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Research Articles on Proliferating Cell Nuclear Antigen (PCNA)
| Target | Proliferating Cell Nuclear Antigen (PCNA) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 162-261 of human PCNA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12004 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R897, D3DW02 |
| UniProt Entry Name | PCNA_HUMAN |
| Gene Symbol | PCNA |
| GeneID | 5111 |
| NCBI Accession | NP_002583.1 |
| KEGG | hsa:5111 |
| String | 9606.ENSP00000368458 |
| Molecular Weight | Calculated MW: 29 kDa Observed MW: 34 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |