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Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibody
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Catalogue No: abx033333
Price:
US$326.25
(Size: 80 µl)
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PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
Research Articles on Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
| Target | Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human PCSK9. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8NBP7 (UniProt, ExPASy) |
| UniProt Secondary AC | A8T640, C0JYY9, Q5PSM5, Q5SZQ2 |
| UniProt Entry Name | PCSK9_HUMAN |
| Gene Symbol | PCSK9 |
| KEGG | hsa:255738 |
| String | 9606.ENSP00000303208 |
| Molecular Weight | Calculated MW: 74.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |