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Procalcitonin (PCT) Antibody
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Catalogue No: abx019248
Price:
US$638.00
(Size: 1 mg)
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Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It is composed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine. Measurement of procalcitonin can be used as a marker of severe sepsis caused by bacteria and generally grades well with the degree of sepsis, although levels of procalcitonin in the blood are very low. PCT has the greatest sensitivity (85%) and specificity (91%) for differentiating patients with systemic inflammatory response syndrome (SIRS) from those with sepsis, when compared with IL-2, IL-6, IL-8, CRP and TNF-alpha. It is a biomarker of bacterial infection which may help gauge the severity and prognosis of patients with CAP. In addition to clinical predictors, PCT may assist in decisions pertaining to timing of discharge from hospital and the discontinuation of antibiotics. PCT (Detection Antibody) is a Mouse Monoclonal antibody against Human PCT. It is recommended to use abx019247 as the capture antibody and abx019248 (this product) as the detection antibody.
Research Articles on Procalcitonin (PCT)
| Target | Procalcitonin (PCT) |
| Clonality | Monoclonal |
| Clone | E518 |
| Reactivity | Human |
| Tested Applications | ELISA, WB, CLIA, TIA |
| Host | Mouse |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant PCT protein. |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | > 95% (HPLC and SDS-PAGE) |
| Purification | Purified by Protein A or Protein G. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Gene Symbol | CALCA |
| Buffer | 0.01 M PBS, 0.15 M NaCl, pH 7.4. Does not contain preservatives. |
| Concentration | 6.58 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |