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Programmed Cell Death Protein 6 (PDCD6) Antibody
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Catalogue No: abx005125
Price:
US$232.00
(Size: 20 µl)
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![Western blot analysis of lysates from wild type(WT) and PDCD6 knockout (KO) 293T(KO) cells, using [KO Validated] PDCD6 Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 1s.](https://www.abbexa.com/image/cache/data/products/18B/abx005125_1-500x500.jpg "Programmed Cell Death Protein 6 (PDCD6) Antibody")
PDCD6 Antibody is a Rabbit Polyclonal antibody against PDCD6. This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.
Research Articles on Programmed Cell Death Protein 6 (PDCD6)
| Target | Programmed Cell Death Protein 6 (PDCD6) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human PDCD6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75340 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RD16, E7ESR3, Q2YDC2, Q5TZS0 |
| UniProt Entry Name | PDCD6_HUMAN |
| Gene Symbol | PDCD6 |
| GeneID | 10016 |
| NCBI Accession | NP_037364.1 |
| KEGG | hsa:10016 |
| String | 9606.ENSP00000264933 |
| Molecular Weight | Calculated MW: 22 kDa Observed MW: 16 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |