Programmed Cell Death Protein 6 (PDCD6) Antibody

PDCD6 Antibody is a Rabbit Polyclonal antibody against PDCD6. This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Target	Programmed Cell Death Protein 6 (PDCD6)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human PDCD6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O75340 (UniProt, ExPASy)
UniProt Secondary AC	B2RD16, E7ESR3, Q2YDC2, Q5TZS0
UniProt Entry Name	PDCD6_HUMAN
Gene Symbol	PDCD6
GeneID	10016
NCBI Accession	NP_037364.1
KEGG	hsa:10016
String	9606.ENSP00000264933
Molecular Weight	Calculated MW: 22 kDa Observed MW: 16 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Programmed Cell Death Protein 6 (PDCD6)

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