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Phosphodiesterase 8B (PDE8B) Antibody
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Catalogue No: abx031349
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Research Articles on Phosphodiesterase 8B (PDE8B)
| Target | Phosphodiesterase 8B (PDE8B) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95263 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5J7V7, Q86XK8, Q8IUJ7, Q8IUJ8, Q8IUJ9, Q8IUK0, Q8N3T2 |
| UniProt Entry Name | PDE8B_HUMAN |
| Gene Symbol | PDE8B |
| KEGG | hsa:8622 |
| String | 9606.ENSP00000264917 |
| Molecular Weight | Calculated MW: 99 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |