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PDGFR Antibody
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Catalogue No: abx025327
Price:
US$623.50
(Size: 100 µl)
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This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]. This antibody is supplied as crude ascites.
Research Articles on PDGFR
| Target | PDGFR |
| Clonality | Monoclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged Human PDGFR protein (Fragment) |
| Isotype | IgG1 Kappa |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09619 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A957, Q8N5L4 |
| UniProt Entry Name | PGFRB_HUMAN |
| KEGG | hsa:5159 |
| String | 9606.ENSP00000261799 |
| Molecular Weight | Calculated MW: 124 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Please enquire. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |