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Platelet Derived Growth Factor Receptor Alpha (PDGFRA) Antibody
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Catalogue No: abx033589
Price:
US$326.25
(Size: 80 µl)
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PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Research Articles on Platelet Derived Growth Factor Receptor Alpha (PDGFRA)
| Target | Platelet Derived Growth Factor Receptor Alpha (PDGFRA) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1048-1077 amino acids from the C-terminal region of human PDGFRA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16234 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RE69, E9PBH0, Q6P4H5, Q96KZ7, Q9UD28 |
| Molecular Weight | Calculated MW: 123 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Chicken PDGFRA. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |