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Platelet Derived Growth Factor Receptor Beta (PDGFRB) Antibody
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Catalogue No: abx001792
Price:
US$203.00
(Size: 20 µl)
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PDGFRB Antibody is a Rabbit Polyclonal antibody against PDGFRB. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Research Articles on Platelet Derived Growth Factor Receptor Beta (PDGFRB)
| Target | Platelet Derived Growth Factor Receptor Beta (PDGFRB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PDGFRB. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09619 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A957, Q8N5L4 |
| UniProt Entry Name | PGFRB_HUMAN |
| Gene Symbol | PDGFRB |
| GeneID | 5159 |
| NCBI Accession | NP_002600.1 |
| KEGG | hsa:5159 |
| String | 9606.ENSP00000261799 |
| Molecular Weight | Calculated MW: 124 kDa Observed MW: 200 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |