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Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody
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Catalogue No: abx011428
Price:
US$420.50
(Size: 100 µl)
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Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. (provided by RefSeq). Tissue specificity: Expressed predominantly in the heart.
Research Articles on Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1)
| Target | Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) |
| Clonality | Monoclonal |
| Reactivity | Human, Monkey, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PDK1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15118 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6T1, B7Z937, D3DPD8, E9PD65, Q308M4 |
| UniProt Entry Name | PDK1_HUMAN |
| GeneID | 5163 |
| KEGG | hsa:5163 |
| String | 9606.ENSP00000376352 |
| Molecular Weight | 44 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |