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Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody
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Catalogue No: abx000875
Price:
US$348.00
(Size: 60 µl)
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PDK1 Antibody is a Rabbit Polyclonal antibody against PDK1. PDK1(pyruvate dehydrogenase kinase isoform 1) is also named as PDHK1 and belongs to the PDK/BCKDK protein kinase family.It inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism(PMID:17683942).Starvation increases islet PDK activity(PMID:11723055).This antibody is speicfic to PDK1.
Research Articles on Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1)
| Target | Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human PDK1/PDHK1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15118 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6T1, B7Z937, D3DPD8, E9PD65, Q308M4 |
| UniProt Entry Name | PDK1_HUMAN |
| Gene Symbol | PDK1 |
| GeneID | 5163 |
| NCBI Accession | NP_002601.1 |
| KEGG | hsa:5163 |
| String | 9606.ENSP00000376352 |
| Molecular Weight | Calculated MW: 49 kDa/51 kDa Observed MW: 49 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |