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Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody
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Catalogue No: abx015964
Price:
US$420.50
(Size: 100 µl)
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The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2.The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression.Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Research Articles on Pancreas/duodenum Homeobox Protein 1 (PDX1)
| Target | Pancreas/duodenum Homeobox Protein 1 (PDX1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PDX1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P52945 (UniProt, ExPASy) |
| UniProt Secondary AC | O60594, Q5VYW2 |
| UniProt Entry Name | PDX1_HUMAN |
| Gene Symbol | PDX1 |
| GeneID | 3651 |
| OMIM | 125853 |
| HGNC | 6107 |
| KEGG | hsa:3651 |
| Ensembl | ENSG00000139515 |
| String | 9606.ENSP00000370421 |
| Molecular Weight | 30.8 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |