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PDZ Domain Containing 3 (PDZD3) Antibody
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Catalogue No: abx029676
Price:
US$326.25
(Size: 80 µl)
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Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).
Research Articles on PDZ Domain Containing 3 (PDZD3)
| Target | PDZ Domain Containing 3 (PDZD3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q86UT5 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3 |
| UniProt Entry Name | NHRF4_HUMAN |
| Gene Symbol | PDZD3 |
| KEGG | hsa:79849 |
| String | 9606.ENSP00000347742 |
| Molecular Weight | Calculated MW: 61 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |