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Retrotransposon-Derived Protein PEG10 (PEG10) Antibody
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Catalogue No: abx002092
Price:
US$217.50
(Size: 20 µl)
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PEG10 Antibody is a Rabbit Polyclonal antibody against PEG10. This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
Research Articles on Retrotransposon-Derived Protein PEG10 (PEG10)
| Target | Retrotransposon-Derived Protein PEG10 (PEG10) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/200 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human PEG10. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q86TG7 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96A68, Q9UPV1 |
| UniProt Entry Name | PEG10_HUMAN |
| Gene Symbol | PEG10 |
| GeneID | 23089 |
| NCBI Accession | NP_001035242.1 |
| KEGG | hsa:23089 |
| String | 9606.ENSP00000418944 |
| Molecular Weight | Calculated MW: 80 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |