Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A) Antibody

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Catalogue No: abx011860
Price: US$797.50
(Size: 96 tests)
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Western blot analysis using PGC-1alpha antibody against human PGC-1alpha (AA: 570-798) recombinant protein. (Expected MW is 70 kDa).
Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A) Antibody Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A) Antibody Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A) Antibody

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Datasheet SDS
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPAR gamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Target Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA
Host Mouse
Recommended dilutions ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human PGC-1alpha expressed in E. coli.
Isotype IgG2b
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UBK2 (UniProt, ExPASy)
UniProt Entry Name PRGC1_HUMAN
Gene Symbol PPARGC1A
GeneID 10891
OMIM 604517
HGNC 9237
Ensembl ENSG00000109819
String 9606.ENSP00000264867
Molecular Weight 91 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A)
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