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Peroxisome Assembly Protein 12 (PEX12) Antibody
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Catalogue No: abx034437
Price:
US$326.25
(Size: 80 µl)
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Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.
Research Articles on Peroxisome Assembly Protein 12 (PEX12)
| Target | Peroxisome Assembly Protein 12 (PEX12) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 131-158 amino acids from the Central region of human PEX12. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00623 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6M2 |
| UniProt Entry Name | PEX12_HUMAN |
| Gene Symbol | PEX12 |
| KEGG | hsa:5193 |
| String | 9606.ENSP00000482609 |
| Molecular Weight | Calculated MW: 40.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow PEX12. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |