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Peroxisomal Biogenesis Factor 19 (PEX19) Antibody
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Catalogue No: abx028024
Price:
US$290.00
(Size: 80 µl)
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This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Research Articles on Peroxisomal Biogenesis Factor 19 (PEX19)
| Target | Peroxisomal Biogenesis Factor 19 (PEX19) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human PEX19. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P40855 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DVE7, Q5QNY4, Q8NI97 |
| UniProt Entry Name | PEX19_HUMAN |
| Gene Symbol | PEX19 |
| KEGG | hsa:5824 |
| String | 9606.ENSP00000357051 |
| Molecular Weight | Calculated MW: 32.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Cow PEX19. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |