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Chk2 (pT383) Antibody
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Catalogue No: abx010984
Price:
US$406.00
(Size: 100 µg)
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Phospho-Chk2 (Thr383) Antibody detects endogenous levels of Chk2 only when phosphorylated at Threonine 383. In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor.
Research Articles on Chk2 (pT383)
| Target | Chk2 (pT383) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O96017 (UniProt, ExPASy) |
| UniProt Entry Name | CHK2_HUMAN |
| Gene Symbol | CHEK2 |
| GeneID | 11200 |
| OMIM | 114480 |
| HGNC | 16627 |
| KEGG | hsa:11200 |
| Ensembl | ENSG00000183765 |
| String | 9606.ENSP00000372023 |
| Enzyme Commission Number | EC 2.7.11.1 |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Note: This product will be discontinued once it is sold out. Please contact us for details. Shipped within 1-2 working days. |
| Note | This product is for research use only. |