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Cyclic Amp-Responsive Element-Binding Protein 1 Phospho-Ser133 (CREB1 pS133) Antibody
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Catalogue No: abx012091
Price:
US$406.00
(Size: 100 µg)
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Cyclic Amp-Responsive Element-Binding Protein 1 Phospho-Ser133 (CREB1 pS133) Antibody is a Rabbit Polyclonal antibody for the detection of Phospho- CREB1 (S133). This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.
Research Articles on Cyclic Amp-Responsive Element-Binding Protein 1 Phospho-Ser133 (CREB1 pS133)
| Target | Cyclic Amp-Responsive Element-Binding Protein 1 Phospho-Ser133 (CREB1 pS133) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Phospho-CREB1-S133 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P16220 (UniProt, ExPASy) |
| UniProt Secondary AC | P21934, Q6V963, Q9UMA7 |
| UniProt Entry Name | CREB1_HUMAN |
| Gene Symbol | CREB1 |
| GeneID | 1385 |
| OMIM | 123810 |
| HGNC | 2345 |
| KEGG | hsa:1385 |
| Ensembl | ENSG00000118260 |
| String | 9606.ENSP00000387699 |
| Molecular Weight | Observed MW: 42 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |