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Mitogen Activated Protein Kinase Kinase Kinase 1 (MAP3K1) Antibody
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Catalogue No: abx216692
Price:
US$406.00
(Size: 100 µg)
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Mitogen Activated Protein Kinase Kinase Kinase 1 (MAP3K1) Antibody is a Rabbit Polyclonal antibody for the detection of MAP3K1. MAP3K1, also named as MAPKKK1, MEKK and MEKK1, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase kinase subfamily. MAP3K1 is a component of a protein kinase signal transduction cascade. MAP3K1 activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. It activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. It catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein.
Research Articles on Mitogen Activated Protein Kinase Kinase Kinase 1 (MAP3K1)
| Target | Mitogen Activated Protein Kinase Kinase Kinase 1 (MAP3K1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Rabbit |
| Recommended dilutions | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | mitogen-activated protein kinase kinase kinase 1 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q13233 (UniProt, ExPASy) |
| UniProt Entry Name | M3K1_HUMAN |
| Gene Symbol | MAP3K1 |
| GeneID | 4214 |
| OMIM | 600982 |
| HGNC | 6848 |
| KEGG | hsa:4214 |
| Ensembl | ENSG00000095015 |
| String | 9606.ENSP00000382423 |
| Molecular Weight | Observed MW: 164 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |