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Serine/Threonine-Protein Kinase MTOR Phospho-Ser2448 (MTOR pS2448) Antibody
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Catalogue No: abx010403
Price:
US$406.00
(Size: 100 µg)
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Serine/Threonine-Protein Kinase MTOR Phospho-Ser2448 (MTOR pS2448) Antibody is a Rabbit Polyclonal antibody for the detection of Phospho- MTOR (S2448). The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Research Articles on Serine/Threonine-Protein Kinase MTOR Phospho-Ser2448 (MTOR pS2448)
| Target | Serine/Threonine-Protein Kinase MTOR Phospho-Ser2448 (MTOR pS2448) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Phospho-MTOR-S2448 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P42345 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3 |
| UniProt Entry Name | MTOR_HUMAN |
| Gene Symbol | MTOR |
| GeneID | 2475 |
| OMIM | 601231 |
| HGNC | 3942 |
| KEGG | hsa:2475 |
| Ensembl | ENSG00000198793 |
| String | 9606.ENSP00000354558 |
| Molecular Weight | Observed MW: 289 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |