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Transcription Factor p65 Phospho-Ser276 (RELA pS276) Antibody
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Catalogue No: abx136147
Price:
US$232.00
(Size: 20 µl)
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Transcription Factor p65 Phospho-Ser276 (RELA pS276) Antibody is a Rabbit Polyclonal antibody against RELA (pS276). NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Research Articles on Transcription Factor p65 Phospho-Ser276 (RELA pS276)
| Target | Transcription Factor p65 Phospho-Ser276 (RELA pS276) |
| Clonality | Polyclonal |
| Target Modification | Ser276 |
| Modification | Phosphorylation |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/100 - 1/500, IHC-P: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Not validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around S276 of human RelA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q04206 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6GTV1, Q6SLK1 |
| UniProt Entry Name | TF65_HUMAN |
| Gene Symbol | RELA |
| GeneID | 5970 |
| OMIM | 164014 |
| NCBI Accession | NP_068810.3 |
| HGNC | 9955 |
| KEGG | hsa:5970 |
| Ensembl | ENSG00000173039 |
| String | 9606.ENSP00000384273 |
| Molecular Weight | Calculated MW: 60 kDa Observed MW: 65 kDa |
| Sequence | RPSDR |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 0.25 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |