Phosphatidylinositol 4-Phosphate 3-Kinase C2 Domain-Containing Subunit Gamma (PI3KC2G) Antibody

PI3KC2G belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.

Target	Phosphatidylinositol 4-Phosphate 3-Kinase C2 Domain-Containing Subunit Gamma (PI3KC2G)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 93-123 amino acids from the N-terminal region of human PI3KC2G.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O75747 (UniProt, ExPASy)
UniProt Secondary AC	A1L3U0
UniProt Entry Name	P3C2G_HUMAN
KEGG	hsa:5288
String	9606.ENSP00000445381
Molecular Weight	Calculated MW: 166 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Phosphatidylinositol 4-Phosphate 3-Kinase C2 Domain-Containing Subunit Gamma (PI3KC2G)

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