Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform (PI3KCG) Antibody

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Catalogue No: abx033932
Price: US$290.00
(Size: 80 µl)

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Datasheet SDS
PIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Target Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform (PI3KCG)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 518-547 amino acids from the Central region of human PI3KCG.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P48736 (UniProt, ExPASy)
UniProt Secondary AC A4D0Q6, Q8IV23, Q9BZC8
UniProt Entry Name PK3CG_HUMAN
KEGG hsa:5294
String 9606.ENSP00000352121
Molecular Weight Calculated MW: 126 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma Isoform (PI3KCG)


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