Protein Inhibitor of Activated STAT 1 (PIAS1) Antibody

REQUEST MORE INFO
Catalogue No: abx026813
Price: US$326.25
(Size: 80 µl)

Orders to United States ship from United States

Reviews: 0 Publications and Reviews
(0 Publications and Reviews)
Protein Inhibitor of Activated STAT 1 (PIAS1) Antibody
Protein Inhibitor of Activated STAT 1 (PIAS1) Antibody Protein Inhibitor of Activated STAT 1 (PIAS1) Antibody

Click on the image to see the image legend

Available Options

* Size:


Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintenance of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.

Target Protein Inhibitor of Activated STAT 1 (PIAS1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 607-637 amino acids from the C-terminal region of human PIAS1.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O75925 (UniProt, ExPASy)
UniProt Secondary AC B2RB67, B3KSY9, C5J4B4, Q147X4, Q99751, Q9UN02
UniProt Entry Name PIAS1_HUMAN
KEGG hsa:8554
String 9606.ENSP00000249636
Molecular Weight Calculated MW: 71.8 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Protein Inhibitor of Activated STAT 1 (PIAS1)
Tags:
(Click to show)