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Protein Inhibitor of Activated STAT2 (PIAS2) Antibody
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Catalogue No: abx004324
Price:
US$217.50
(Size: 20 µl)
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PIAS2 Antibody is a Rabbit Polyclonal antibody against PIAS2. This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.
Research Articles on Protein Inhibitor of Activated STAT2 (PIAS2)
| Target | Protein Inhibitor of Activated STAT2 (PIAS2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 420-621 of human PIAS2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75928 (UniProt, ExPASy) |
| UniProt Secondary AC | O75927, Q96BT5, Q96KE3 |
| UniProt Entry Name | PIAS2_HUMAN |
| Gene Symbol | PIAS2 |
| GeneID | 9063 |
| NCBI Accession | NP_004662.2 |
| KEGG | hsa:9063 |
| String | 9606.ENSP00000465676 |
| Molecular Weight | Calculated MW: 68 kDa Observed MW: 75 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |