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Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2) Antibody
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Catalogue No: abx240142
Price:
US$406.00
(Size: 100 µg)
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Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2) Antibody is a Rabbit Polyclonal antibody for the detection of Piezo2. The protein encoded by this gene contains more than thirty transmembrane domains and likely functions as part of mechanically-activated (MA) cation channels. These channels serve to connect mechanical forces to biological signals. The encoded protein quickly adapts MA currents in somatosensory neurons. Defects in this gene are a cause of type 5 distal arthrogryposis. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Research Articles on Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2)
| Target | Piezo-Type Mechanosensitive Ion Channel Component 2 (PIEZO2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Rabbit |
| Recommended dilutions | IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Piezo-type mechanosensitive ion channel component 2 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q9H5I5 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z812, M4GPJ9, Q6ZS91, Q8N787, Q8NAR6, Q9H5R4 |
| UniProt Entry Name | PIEZ2_HUMAN |
| Gene Symbol | PIEZO2 |
| GeneID | 63895 |
| KEGG | hsa:63895 |
| String | 9606.ENSP00000421377 |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |