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Quinone Oxidoreductase PIG3 (TP53I3) Antibody
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Catalogue No: abx030896
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
Research Articles on Quinone Oxidoreductase PIG3 (TP53I3)
| Target | Quinone Oxidoreductase PIG3 (TP53I3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human PIG3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q53FA7 (UniProt, ExPASy) |
| UniProt Secondary AC | D6W533, O14679, O14685, Q38G78, Q6JLE7, Q9BWB8 |
| UniProt Entry Name | QORX_HUMAN |
| KEGG | hsa:9540 |
| String | 9606.ENSP00000238721 |
| Molecular Weight | Calculated MW: 35.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |