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Phosphatidylinositol Glycan Anchor Biosynthesis Class A (PIGA) Antibody
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Catalogue No: abx026766
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.
Research Articles on Phosphatidylinositol Glycan Anchor Biosynthesis Class A (PIGA)
| Target | Phosphatidylinositol Glycan Anchor Biosynthesis Class A (PIGA) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 455-484 amino acids from the C-terminal region of human PIGA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P37287 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E0V2, Q16025, Q16250 |
| UniProt Entry Name | PIGA_HUMAN |
| Gene Symbol | PIGA |
| KEGG | hsa:5277 |
| String | 9606.ENSP00000369820 |
| Molecular Weight | Calculated MW: 54.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |