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Serine/Threonine-Protein Kinase Pim-2 (PIM2) Antibody
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Catalogue No: abx033773
Price:
US$326.25
(Size: 80 µl)
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Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
Research Articles on Serine/Threonine-Protein Kinase Pim-2 (PIM2)
| Target | Serine/Threonine-Protein Kinase Pim-2 (PIM2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100, IP: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 277-308 amino acids from the C-terminal region of human PIM2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9P1W9 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K4G6, Q99739 |
| UniProt Entry Name | PIM2_HUMAN |
| NCBI Accession | NP_006866.2 |
| String | 9606.ENSP00000365692 |
| Molecular Weight | Calculated MW: 34.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |