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Serine/Threonine-Protein Kinase PINK1, Mitochondrial (PINK1) Antibody
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Catalogue No: abx032822
Price:
US$326.25
(Size: 80 µl)
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Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
Research Articles on Serine/Threonine-Protein Kinase PINK1, Mitochondrial (PINK1)
| Target | Serine/Threonine-Protein Kinase PINK1, Mitochondrial (PINK1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 118-147 amino acids from the N-terminal region of human PINK1 (PARK6). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BXM7 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N6T9, Q8NBU3, Q96DE4 |
| UniProt Entry Name | PINK1_HUMAN |
| Gene Symbol | PINK1 |
| NCBI Accession | NP_115785.1 |
| String | 9606.ENSP00000364204 |
| Molecular Weight | Calculated MW: 62.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |