PDZ Protein Interacting Specifically With TC10 (PIST) Antibody

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Catalogue No: abx033275
Price: US$326.25
(Size: 80 µl)

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PDZ Protein Interacting Specifically With TC10 (PIST) Antibody
PDZ Protein Interacting Specifically With TC10 (PIST) Antibody PDZ Protein Interacting Specifically With TC10 (PIST) Antibody

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Datasheet SDS
PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner. PIST, a PDZ domain-containing Golgi protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.

Target PDZ Protein Interacting Specifically With TC10 (PIST)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 361-390 amino acids from the C-terminal region of human PIST.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9HD26 (UniProt, ExPASy)
UniProt Secondary AC A6NM30, Q59FS4, Q969U8
UniProt Entry Name GOPC_HUMAN
String 9606.ENSP00000357484
Molecular Weight Calculated MW: 50.5 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on PDZ Protein Interacting Specifically With TC10 (PIST)


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