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PKC zeta Antibody
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Catalogue No: abx033125
Price:
US$326.25
(Size: 80 µl)
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Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a constitutive kinase activity which is independent of calcium, and PKC activators, phosphatidylserine and diacylglycerol. Furthermore, it is insensitive to PKC inhibitors and cannot be activated by phorbol ester. The structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC.
Research Articles on PKC zeta
| Target | PKC zeta |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 166-197 amino acids from the N-terminal region of human PKC zeta. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q05513 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K4N0, A8MU64, B7Z2J7, E9PCW2, Q15207, Q5SYT5, Q969S4 |
| UniProt Entry Name | KPCZ_HUMAN |
| NCBI Accession | NP_001028753.1 NP_001028754.1 NP_001229803.1 NP_002735.3 |
| KEGG | hsa:5590 |
| String | 9606.ENSP00000367830 |
| Molecular Weight | Calculated MW: 67.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |