Pyruvate Kinase PKM (PKM) Antibody

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Target	Pyruvate Kinase PKM (PKM)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 460-489 amino acids from the C-terminal region of human PKM2.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P14618 (UniProt, ExPASy)
Molecular Weight	Calculated MW: 57.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rabbit PKM.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Pyruvate Kinase PKM (PKM)

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