Plakophilin 2 (PKP2) Antibody

PKP2 Antibody is a Rabbit Polyclonal antibody against PKP2. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.

Target	Plakophilin 2 (PKP2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 578-837 of human PKP2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99959 (UniProt, ExPASy)
UniProt Secondary AC	A0AV37, B8QFA1, B8QGS6, B8QGS7, D3DUW9, Q4VC01, Q99960
UniProt Entry Name	PKP2_HUMAN
Gene Symbol	PKP2
GeneID	5318
NCBI Accession	NP_001005242.2
KEGG	hsa:5318
String	9606.ENSP00000070846
Molecular Weight	Calculated MW: 97 kDa Observed MW: 95-105 kDa
Buffer	PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Plakophilin 2 (PKP2)

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