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PLCG1 (pY783) Antibody
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Catalogue No: abx000216
Price:
US$246.50
(Size: 20 µl)
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PLCG1 (pY783) Antibody is a Rabbit Polyclonal antibody against PLCG1 (pY783). The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on PLCG1 (pY783)
| Target | PLCG1 (pY783) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic phosphorylated peptide around Y783 of human PLC gamma 1 (PLCG1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P19174 (UniProt, ExPASy) |
| UniProt Secondary AC | B7ZLY7, B9EGH4, E1P5W4, Q2V575 |
| UniProt Entry Name | PLCG1_HUMAN |
| Gene Symbol | PLCG1 |
| GeneID | 5335 |
| NCBI Accession | NP_877963.1 |
| KEGG | hsa:5335 |
| String | 9606.ENSP00000244007 |
| Molecular Weight | Calculated MW: 149 kDa Observed MW: 155 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |