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Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody
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Catalogue No: abx001794
Price:
US$203.00
(Size: 20 µl)
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PLCG2 Antibody is a Rabbit Polyclonal antibody against PLCG2. The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Research Articles on Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2)
| Target | Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLC gamma 2 (PLCG2). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16885 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DUL3, Q3ZTS2, Q59H45, Q969T5 |
| UniProt Entry Name | PLCG2_HUMAN |
| Gene Symbol | PLCG2 |
| GeneID | 5336 |
| NCBI Accession | NP_002652.2 |
| KEGG | hsa:5336 |
| String | 9606.ENSP00000482457 |
| Molecular Weight | Calculated MW: 148 kDa Observed MW: 175 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |