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Procollagen Lysine-1,2-Oxoglutarate-5-Dioxygenase 1 (PLOD1) Antibody
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Catalogue No: abx026944
Price:
US$326.25
(Size: 80 µl)
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Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity.
Research Articles on Procollagen Lysine-1,2-Oxoglutarate-5-Dioxygenase 1 (PLOD1)
| Target | Procollagen Lysine-1,2-Oxoglutarate-5-Dioxygenase 1 (PLOD1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/10 - 1/50, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human PLOD1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02809 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DR87, Q96AV9, Q9H132 |
| UniProt Entry Name | PLOD1_HUMAN |
| Gene Symbol | PLOD1 |
| GeneID | 5351 |
| OMIM | 153454 |
| HGNC | 9081 |
| KEGG | hsa:5351 |
| Ensembl | ENSG00000083444 |
| String | 9606.ENSP00000196061 |
| Molecular Weight | Calculated MW: 83.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse PLOD1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |