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Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2) Antibody
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Catalogue No: abx005269
Price:
US$348.00
(Size: 60 µl)
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PLOD2 Antibody is a Rabbit Polyclonal antibody against PLOD2. The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2)
| Target | Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PLOD2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00469 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KWS3, Q59ED2, Q8N170 |
| UniProt Entry Name | PLOD2_HUMAN |
| Gene Symbol | PLOD2 |
| GeneID | 5352 |
| NCBI Accession | NP_000926.2 |
| KEGG | hsa:5352 |
| String | 9606.ENSP00000282903 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |