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Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 3 (PLOD3) Antibody
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Catalogue No: abx026982
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.
Research Articles on Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 3 (PLOD3)
| Target | Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 3 (PLOD3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 78-105 amino acids from the N-terminal region of human PLOD3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60568 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6W6, Q540C3 |
| UniProt Entry Name | PLOD3_HUMAN |
| Gene Symbol | PLOD3 |
| KEGG | hsa:8985 |
| String | 9606.ENSP00000223127 |
| Molecular Weight | Calculated MW: 84.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |