PMS1 Homolog 1, Mismatch Repair System Component (PMS1) Antibody

This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Target	PMS1 Homolog 1, Mismatch Repair System Component (PMS1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 694-722 amino acids from the C-terminal region of human PMS1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P54277 (UniProt, ExPASy)
UniProt Secondary AC	D3DPI1, Q4VAL4, Q5FBZ3, Q5FBZ6, Q5FBZ8
UniProt Entry Name	PMS1_HUMAN
KEGG	hsa:5378
String	9606.ENSP00000406490
Molecular Weight	Calculated MW: 106 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on PMS1 Homolog 1, Mismatch Repair System Component (PMS1)

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