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PMS1 Homolog 1, Mismatch Repair System Component (PMS1) Antibody
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Catalogue No: abx001795
Price:
US$203.00
(Size: 20 µl)
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PMS1 Antibody is a Rabbit Polyclonal antibody against PMS1. This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
Research Articles on PMS1 Homolog 1, Mismatch Repair System Component (PMS1)
| Target | PMS1 Homolog 1, Mismatch Repair System Component (PMS1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 405-619 of human PMS1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54277 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DPI1, Q4VAL4, Q5FBZ3, Q5FBZ6, Q5FBZ8 |
| UniProt Entry Name | PMS1_HUMAN |
| Gene Symbol | PMS1 |
| GeneID | 5378 |
| NCBI Accession | NP_000525.1 |
| KEGG | hsa:5378 |
| String | 9606.ENSP00000406490 |
| Molecular Weight | Calculated MW: 106 kDa Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |