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Mismatch Repair Endonuclease PMS2 (PMS2) Antibody
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Catalogue No: abx005270
Price:
US$377.00
(Size: 60 µl)
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PMS2 Antibody is a Rabbit Polyclonal antibody against PMS2. This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.
Research Articles on Mismatch Repair Endonuclease PMS2 (PMS2)
| Target | Mismatch Repair Endonuclease PMS2 (PMS2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PMS2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P54278 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R610, Q52LH6, Q5FBW9, Q5FBX1, Q5FBX2, Q75MR2 |
| UniProt Entry Name | PMS2_HUMAN |
| Gene Symbol | PMS2 |
| GeneID | 5395 |
| NCBI Accession | NP_000526.2 |
| KEGG | hsa:5395 |
| String | 9606.ENSP00000265849 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |